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The coronavirus disease 2019 (COVID-19) pandemic and the coming transition to a postpandemic world where COVID-19 will likely remain as an endemic disease present a host of challenges and opportunities in epidemiologic research. Read the paper at https://academic.oup.com/aje/article/190/1/17/5874603
https://www.lupop.lu.se/article/what-now-epidemiology-wake-pandemic - 2025-12-23
Suppose that an investigator wants to estimate an association between a continuous exposure variable and an outcome, adjusting for a set of confounders. If the exposure variable suffers classical measurement error, in which the measured exposures are distributed with independent error around the true exposure, then an estimate of the covariate-adjusted exposure-outcome association may be biased. R
https://www.lupop.lu.se/article/reducing-bias-due-exposure-measurement-error-using-disease-risk-scores - 2025-12-23
In aspiring to be discerning epidemiologists, we must learn to think critically about the fundamental concepts in our field and be able to understand and apply many of the novel methods being developed today. We must also find effective ways to teach both basic and advanced topics in epidemiology to graduate students, in a manner that goes beyond simple provision of knowledge. Read the paper at ht
https://www.lupop.lu.se/article/simulation-tool-teaching-and-learning-epidemiologic-methods - 2025-12-23
Factorial Mendelian randomization is the use of genetic variants to answer questions about interactions. Although the approach has been used in applied investigations, little methodological advice is available on how to design or perform a factorial Mendelian randomization analysis. Read the paper at https://academic.oup.com/ije/article/49/4/1147/5542600?rss=1
https://www.lupop.lu.se/article/factorial-mendelian-randomization-using-genetic-variants-assess-interactions - 2025-12-23
Unmeasured confounding can bias the relationship between exposure and outcome. Sensitivity analyses generate bias-adjusted measures but these are not much used; this may change with the availability of the E-value (for evidence for causality in observational studies), appealing for its ease of calculation. Read the paper at https://academic.oup.com/ije/article/49/5/1509/5913108
https://www.lupop.lu.se/article/bias-factor-maximum-bias-and-e-value-insight-and-extended-applications - 2025-12-23
We illustrate the method and some potential choices using data from England for men diagnosed with melanoma. Various marginal measures are presented and compared. Read the paper at https://academic.oup.com/ije/article/49/5/1614/5896134
The PhD position is linked to the research project The long reach of the neighborhood: Health, education and earnings in Landskrona, Sweden, 1904-2015, funded by Handelsbankens forskningsstiftelser. The PhD student will work in this project in collaboration with other project members and will be affiliated with the Centre for Economic Demography at LUSEM (CED, www.ed.lu.se). Read more and apply he
https://www.lupop.lu.se/article/phd-position-economic-history-neighborhood-effects-over-life-course - 2025-12-23
Find out how GDPR will affect you and your research! More information, including programme, here.
https://www.lupop.lu.se/article/gdpr-event - 2025-12-23
This paper describes the multiform, wave-missing and two-method designs, including their benefits, their impact on bias and power, and other factors that must be taken into consideration when implementing them in an epidemiological study design. Read the paper at https://academic.oup.com/ije/article/49/5/1702/5827680
https://www.lupop.lu.se/article/reflection-modern-methods-planned-missing-data-designs-epidemiological-research - 2025-12-23
This study extends TCAL by disentangling causes of death contributions. The strength of the approach is that it allows identification of mortality differences in cohorts with members still alive, as well as identification of which ages and causes of death contribute to mortality differentials between populations. Read the paper at https://academic.oup.com/ije/article/49/5/1712/5721433
https://www.lupop.lu.se/article/reflection-modern-methods-cause-death-decomposition-cohort-survival-comparisons - 2025-12-23
New research supports the theory that certain viral infections are of importance in the development of type 1 diabetes. An international research team has discovered that young children with an increased genetic risk of type 1 diabetes had an increased risk of developing diabetes-related autoantibodies in connection with Covid-19 infection. Swedish children have contributed to the study which has
https://www.ludc.lu.se/article/new-study-virus-importance-development-type-1-diabetes - 2025-12-23
Lund University Diabetes Centre’s Scientific Advisory Board give researchers valuable feedback on ongoing research. Frances Ashcroft and Flemming Pociot from the board were invited to the LUDC retreat in the city of Helsingborg recently and they were impressed by the range of the research being performed at the centre. Research within type 1 diabetes specifically caught their attention. Frances As
https://www.ludc.lu.se/article/scientific-advisory-board-important-contributions-within-type-1-diabetes-research - 2025-12-23
An international consensus report on diabetes identifies the potential for diabetes screening, better classification of type 2 diabetes, and biomarkers that can predict cardiovascular disease. The report also highlights that more evidence is needed before it is possible to provide individualised treatment to all patients. The report is based on a large collaboration between 28 universities worldwi
https://www.ludc.lu.se/article/new-report-highlights-opportunities-and-challenges-precision-diabetes-medicine - 2025-12-23
How do heritability and the fetal environment affect the risk for the child to develop type 2 diabetes? This is a question that Rashmi Prasad studies in her research projects that that may lead to individualised prevention measures. She will be awarded this year’s recipient Medeon stipend on the World Diabetes Day Skåne event on November 14. Diabetes researcher Rashmi Prasad at Lund University Dia
https://www.ludc.lu.se/article/research-inherited-type-2-diabetes-awarded - 2025-12-23
Diabetes researcher and cardiologist Isabel Goncalves at Lund University Diabetes Centre (LUDC) has teamed up with ultrasound researchers at the Faculty of Engineering at Lund University (LTH) to identify dangerous atherosclerotic plaques at an early stage. The team is now being awarded Lund University’s and Sparbanken Skåne’s Future Innovations Award to develop their idea further. In atherosclero
https://www.ludc.lu.se/article/innovation-aims-identify-dangerous-atherosclerotic-plaques-wins-prize - 2025-12-23
Do epigenetic changes cause type 2 diabetes, or do the changes occur only after a person has become ill? A new study by researchers at Lund University provides increased support for the idea that epigenetic changes can cause type 2 diabetes. The researchers behind the new findings published in Nature Communications now aim to develop methods for disease prevention. We inherit our genes from our pa
https://www.ludc.lu.se/article/epigenetic-changes-can-cause-type-2-diabetes - 2025-12-23
An international team of researchers has identified 13 biomarkers that significantly improve the ability to accurately predict cardiovascular disease risk in people with type 2 diabetes. The analysis was led by Lund University, Johns Hopkins University, and the Chinese University of Hong Kong. The study was published in Communications Medicine. Although people with type 2 diabetes are two times mo
https://www.ludc.lu.se/article/new-study-biomarkers-improve-prediction-cardiovascular-disease-type-2-diabetes - 2025-12-23
Much research on diabetes focuses on understanding what happens when the insulin-producing cells are destroyed. Researchers at Lund University have instead chosen to investigate what protects the insulin-producing cells. Their research shows that a protein of the immune system protects the insulin-producing cells from inflammation and death. The study, published in PNAS, is an example of basic res
https://www.ludc.lu.se/article/protein-protects-insulin-producing-cells - 2025-12-23
Diabetes researchers Allan Vaag and Lena Eliasson are the new coordinators of Lund University Diabetes Centre (LUDC) and the strategic research area EXODIAB (Excellence of Diabetes Research in Sweden). Over the next years, they will work to strengthen and further develop ongoing collaborations. Coordinator Allan Vaag and Vice Coordinator Lena Eliasson are new leaders since the beginning of the yea
https://www.ludc.lu.se/article/new-coordinators-strategic-research-area-diabetes - 2025-12-23
Do you think that people with obesity have themselves to blame? Tune H Pers tries to dispel persistent myths through his research on the brain's role in the development of obesity. The diabetes researcher at the University of Copenhagen is now awarded the Leif C. Groop award for his research on obesity and type 2 diabetes. Justification for awarding"Tune H Pers receives the Leif C. Groop Award for
https://www.ludc.lu.se/article/tune-h-pers-receives-award-outstanding-research-obesity-and-diabetes - 2025-12-23
